An Integrated Regulatory Network Based on Comprehensive Analysis of mRNA Expression, Gene Methylation and Expression of Long Non-coding RNAs (lncRNAs) in Myelodysplastic Syndromes

An Integrated Regulatory Network Based on Comprehensive Analysis of mRNA Expression, Gene Methylation and Expression of Long Non-coding RNAs (lncRNAs) in Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are a heterogeneous group of disorders characterized by ineffective hematopoiesis, defective differentiation of hematopoietic precursors, and expansion of the abnormal clones. The prevalence of MDS has raised great concerns worldwide, but its pathogenetic mechanisms r...

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Bibliographic Details
Main Authors: Xiaoli Zhao, Hua Yin, Nianyi Li, Yu Zhu, Wenyi Shen, Sixuan Qian, Guangsheng He, Jianyong Li, Xiaoqin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
myelodysplastic syndromes
differentially expressed genes
methylated genes
microRNAs
lncRNAs
regulatory network
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00200/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00200/full

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