Evidence That Phosphorylation of the α-Subunit of eIF2 Does Not Essentially Inhibit mRNA Translation in Wheat Germ Cell-Free System

Evidence That Phosphorylation of the α-Subunit of eIF2 Does Not Essentially Inhibit mRNA Translation in Wheat Germ Cell-Free System

A mechanism based on reversible phosphorylation of the α-subunit of eukaryotic initiation factor 2 (eIF2α) has been confirmed as an important regulatory pathway for the inhibition of protein synthesis in mammalian and yeast cells, while plants constitute the significant exception. We studied the ind...

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Bibliographic Details
Main Authors: Andrey V. Zhigailov, Alena M. Alexandrova, Anna S. Nizkorodova, Gulshan E. Stanbekova, Ruslan V. Kryldakov, Oxana V. Karpova, Nailya S. Polimbetova, Nigel G. Halford, Bulat K. Iskakov
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Plant Science
Subjects:
wheat
eIF2
eIF2α kinase
GCN2
PKR
eIF2B
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2020.00936/full

Internet

https://www.frontiersin.org/article/10.3389/fpls.2020.00936/full

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