Redox Post-translational Modifications of Protein Thiols in Brain Aging and Neurodegenerative Conditions—Focus on S-Nitrosation
Reactive oxygen species and reactive nitrogen species (RONS) are by-products of aerobic metabolism. RONS trigger a signaling cascade that can be transduced through oxidation-reduction (redox)-based post-translational modifications (redox PTMs) of protein thiols. This redox signaling is essential for...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2020-09-01
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Series: | Frontiers in Aging Neuroscience |
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Online Access: | https://www.frontiersin.org/article/10.3389/fnagi.2020.00254/full |