miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway

miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway

Nasopharyngeal carcinoma (NPC) is prevalent in East and Southeast Asia. In a previous study, Epstein-Barr virus (EBV)-miR-BART22 induces tumor metastasis and stemness and is significantly involved in NPC progression. In the present study, we observed that miR-4721 is induced by EBV-miR-BART22 throug...

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Bibliographic Details
Main Authors: ZiBo Tang, WeiFeng Chen, Yan Xu, Xian Lin, Xiong Liu, YongHao Li, YiYi Liu, ZhiJian Luo, Zhen Liu, WeiYi Fang, MengYang Zhao
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
epithelial cell carcinoma
EBV
onco-miR
cell cycle
proliferation
tumor marker
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302924

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http://www.sciencedirect.com/science/article/pii/S2162253120302924

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