Classification of RNA backbone conformations into rotamers using 13C′ chemical shifts: exploring how far we can go

The conformational space of the ribose-phosphate backbone is very complex as it is defined in terms of six torsional angles. To help delimit the RNA backbone conformational preferences, 46 rotamers have been defined in terms of these torsional angles. In the present work, we use the ribose experimen...

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Bibliographic Details
Main Authors: Alejandro A. Icazatti, Juan M. Loyola, Igal Szleifer, Jorge A. Vila, Osvaldo A. Martin
Format: Article
Language:English
Published: PeerJ Inc. 2019-10-01
Series:PeerJ
Subjects:
RNA
DFT
Online Access:https://peerj.com/articles/7904.pdf