Resveratrol Targets Sphingolipid Metabolism to Induce Growth Inhibition in FLT3 ITD Acute Myeloid Leukemia

Sphingolipids are important signaling lipids which play crucial roles to determine the cell fate. Ceramide, apoptotic central molecule of sphingolipid metabolism, which is produced through <i>de novo</i> pathway by serine palmitoyl transferase (SPT) and can be converted to antiapoptotic...

Full description

Bibliographic Details
Main Authors: Nur Şebnem Ersöz, Aysun Adan
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/40/1/4