Resveratrol Targets Sphingolipid Metabolism to Induce Growth Inhibition in FLT3 ITD Acute Myeloid Leukemia
Sphingolipids are important signaling lipids which play crucial roles to determine the cell fate. Ceramide, apoptotic central molecule of sphingolipid metabolism, which is produced through <i>de novo</i> pathway by serine palmitoyl transferase (SPT) and can be converted to antiapoptotic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | Proceedings |
Subjects: | |
Online Access: | https://www.mdpi.com/2504-3900/40/1/4 |