Transcriptional and translational‐uncoupling in regulation of the CXCL12 and its receptors CXCR4, 7 in THP‐1 monocytes and macrophages
Abstract Introduction The chemokine CXCL12 and its receptors CXCR4 and 7 play crucial roles in the immune system. In the present study, regulation of this pathway was further examined using the in‐vitro model of undifferentiated human THP‐1 monocytes (u‐THP‐1) and phorbol 12‐myristate 13‐acetate (PM...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-03-01
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Series: | Immunity, Inflammation and Disease |
Subjects: | |
Online Access: | https://doi.org/10.1002/iid3.199 |