Co-Positivity for Anti-dsDNA, -Nucleosome and -Histone Antibodies in Lupus Nephritis Is Indicative of High Serum Levels and Severe Nephropathy.

Co-Positivity for Anti-dsDNA, -Nucleosome and -Histone Antibodies in Lupus Nephritis Is Indicative of High Serum Levels and Severe Nephropathy.

OBJECTIVE:To characterize the significance of correlated autoantibodies in systemic lupus erythematosus (SLE) and its complication lupus nephritis (LN) in a large cohort of patients. METHODS:Clinical data were statistically analyzed in 1699 SLE patients with or without nephritis who were diagnosed a...

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Main Authors: Jinfeng Yang, Zhaozhen Xu, Manshu Sui, Jihua Han, Lijie Sun, Xiuzhi Jia, Haiyu Zhang, Changsong Han, Xiaoming Jin, Fei Gao, Yanhong Liu, Yang Li, Jianbin Cao, Hong Ling, Fengmin Zhang, Huan Ren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605492?pdf=render

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http://europepmc.org/articles/PMC4605492?pdf=render

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