The Role of Wnt/β-Catenin Pathway Mediators in Aortic Valve Stenosis

Aortic valve stenosis (AVS) is a prevailing and life-threatening cardiovascular disease in adults over 75 years of age. However, the molecular mechanisms governing the pathogenesis of AVS are yet to be fully unraveled. With accumulating evidence that Wnt signaling plays a key role in the development...

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Bibliographic Details
Main Authors: Kashif Khan, Bin Yu, Chrystina Kiwan, Yousif Shalal, Sabin Filimon, Megan Cipro, Dominique Shum-Tim, Renzo Cecere, Adel Schwertani
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00862/full