Alignment of stroma fibers, microvessel density and immune cell populations determine overall survival in pancreatic cancer-An analysis of stromal morphology.

<h4>Introduction</h4>The aim of this study was to define histo-morphological stroma characteristics by analyzing stromal components, and to evaluate their impact on local and systemic tumor spread and overall survival in pancreatic ductal adenocarcinoma (PDAC).<h4>Methods and mater...

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Bibliographic Details
Main Authors: Louisa Bolm, Petro Zghurskyi, Hryhoriy Lapshyn, Ekaterina Petrova, Sergiy Zemskov, Yogesh K Vashist, Steffen Deichmann, Kim C Honselmann, Peter Bronsert, Tobias Keck, Ulrich F Wellner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234568