Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

Preimplantation embryos undergo extensive transcriptomic and epigenomic remodeling. Here the authors assay open chromatin in bovine oocytes, embryos, and embryonic stem cells, and compare the transcriptomes and epigenomes of cattle, human and mouse embryos, revealing species-specific regulation of g...

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Bibliographic Details
Main Authors: Michelle M. Halstead, Xin Ma, Chuan Zhou, Richard M. Schultz, Pablo J. Ross
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18508-3