The potential therapeutic effect of guanosine after cortical focal ischemia in rats.

The potential therapeutic effect of guanosine after cortical focal ischemia in rats.

BACKGROUND AND PURPOSE: Stroke is a devastating disease. Both excitotoxicity and oxidative stress play important roles in ischemic brain injury, along with harmful impacts on ischemic cerebral tissue. As guanosine plays an important neuroprotective role in the central nervous system, the purpose of...

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Bibliographic Details
Main Authors: Gisele Hansel, Denise Barbosa Ramos, Camila Aguilar Delgado, Débora Guerini Souza, Roberto Farina Almeida, Luis Valmor Portela, André Quincozes-Santos, Diogo Onofre Souza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938812?pdf=render

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http://europepmc.org/articles/PMC3938812?pdf=render

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