Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients

Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients

Abstract The breakdown of nasal epithelial barrier occurs in allergic rhinitis (AR) patients. Impairment of cell junction molecules including tight junctions (TJs) and desmosomes plays causative roles in the pathogenesis of AR. In this study, we investigated the transcript expression levels of TJs i...

Full description

Bibliographic Details
Main Authors: Siti Muhamad Nur Husna, Che Othman Siti Sarah, Hern-Tze Tina Tan, Norasnieda Md. Shukri, Noor Suryani Mohd Ashari, Kah Keng Wong
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79208-y

Internet

https://doi.org/10.1038/s41598-020-79208-y

Similar Items