Exploiting human memory B cell heterogeneity for improved vaccine efficacy

The major goal in vaccination is establishment of long-term, prophylactic humoral memory to a pathogen. Two major components to long-lived humoral memory are plasma cells for the production of specific immunoglobulin and memory B cells that survey for their specific antigen in the periphery for lat...

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Bibliographic Details
Main Authors: Noel Thomas Pauli, Carole J. Henry Dunand, Patrick C. Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00077/full