Identification of toxicity pathway of diesel particulate matter using AOP of PPARγ inactivation leading to pulmonary fibrosis

Identification of toxicity pathway of diesel particulate matter using AOP of PPARγ inactivation leading to pulmonary fibrosis

Diesel particulate matter (DPM), a major subset of urban fine particulate matter (PM2.5), raises huge concerns for human health and has therefore been classified as a group 1 carcinogen by the International Agency for Research on Cancer (IARC). However, as DPM is a complex mixture of various chemica...

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Bibliographic Details
Main Authors: Jaeseong Jeong, Su-yong Bae, Jinhee Choi
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Environment International
Subjects:
Diesel particulate matter
Adverse Outcome Pathway
ToxCast
Deep learning
Mixture toxicity
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412020322947

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http://www.sciencedirect.com/science/article/pii/S0160412020322947

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