Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells

Lymphangiogenesis occurs in the context of systemic inflammation and development but has not been reported for the lymphatics that surround the CNS. Here the authors show that in the context of experimental autoimmune encephatlitis, lymphangiogenesis occurs at the cribriform plate, but not the menin...

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Bibliographic Details
Main Authors: Martin Hsu, Aditya Rayasam, Julie A. Kijak, Yun Hwa Choi, Jeffrey S. Harding, Sarah A. Marcus, William J. Karpus, Matyas Sandor, Zsuzsanna Fabry
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08163-0