Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts.

Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts.

Amyloid formation is historically associated with cytotoxicity, but many organisms produce functional amyloid fibers (e.g., curli) as a normal part of cell biology. Two E. coli genes in the curli operon encode the chaperone-like proteins CsgC and CsgE that both can reduce in vitro amyloid formation...

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Bibliographic Details
Main Authors: Erik Chorell, Emma Andersson, Margery L Evans, Neha Jain, Anna Götheson, Jörgen Åden, Matthew R Chapman, Fredrik Almqvist, Pernilla Wittung-Stafshede
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605646?pdf=render

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http://europepmc.org/articles/PMC4605646?pdf=render

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