Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage
<p>Abstract</p> <p>Mammalian constitutive photomorphogenic 1 (COP1) is a p53 E3 ubiquitin ligase involved in regulating p53 protein level. In plants, the dynamic cytoplasm/nucleus distribution of COP1 is important for its function in terms of catalyzing the degradation of target pr...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-09-01
|
| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/9/1/243 |