Nuclear factor-kappaB regulates the transcription of NADPH oxidase 1 in human alveolar epithelial cells

Nuclear factor-kappaB regulates the transcription of NADPH oxidase 1 in human alveolar epithelial cells

Abstract Objective Acute lung injury (ALI) is characterized by inflammation and oxidative stress. Nuclear factor-kappaB (NF-κB) mediates the expression of various inflammation-related genes, including the NADPH oxidase family. This study aimed to identify the potential regulatory role of NF-κB on NA...

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Bibliographic Details
Main Authors: Weijing Wu, Li Li, Xiaoshan Su, Zhixing Zhu, Xiaoping Lin, Jiamin Zhang, Zesen Zhuang, Hongyi Cai, Wenjie Huang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Pulmonary Medicine
Subjects:
Acute lung injury
Nuclear factor-kappaB
NADPH oxidase
Tumor necrosis factor-α
NOX1
Reactive oxygen species
Online Access:https://doi.org/10.1186/s12890-021-01464-z

Internet

https://doi.org/10.1186/s12890-021-01464-z

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