Mass Cytometry Phenotyping of Human Granulocytes Reveals Novel Basophil Functional Heterogeneity

Mass Cytometry Phenotyping of Human Granulocytes Reveals Novel Basophil Functional Heterogeneity

Summary: Basophils, the rarest granulocyte, play critical roles in parasite- and allergen-induced inflammation. We applied mass cytometry (CyTOF) to simultaneously asses 44 proteins to phenotype and functionally characterize neutrophils, eosinophils, and basophils from 19 healthy donors. There was m...

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Bibliographic Details
Main Authors: Nora Vivanco Gonzalez, John-Paul Oliveria, Dmitry Tebaykin, Geoffrey T. Ivison, Kaori Mukai, Mindy M. Tsai, Luciene Borges, Kari C. Nadeau, Stephen J. Galli, Albert G. Tsai, Sean C. Bendall
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:iScience
Subjects:
Immunology
Systems Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309214

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http://www.sciencedirect.com/science/article/pii/S2589004220309214

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