Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.

Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.

Gene targeting in most of human somatic cell lines has been labor-intensive because of low homologous recombination efficiency. The development of an experimental system that permits a facile evaluation of gene targeting efficiency in human somatic cell lines is the first step towards the improvemen...

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Bibliographic Details
Main Authors: Sivasundaram Karnan, Yuko Konishi, Akinobu Ota, Miyuki Takahashi, Lkhagvasuren Damdindorj, Yoshitaka Hosokawa, Hiroyuki Konishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466256?pdf=render

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http://europepmc.org/articles/PMC3466256?pdf=render

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