Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells.

Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells.

Coibamide A is an N-methyl-stabilized depsipeptide that was isolated from a marine cyanobacterium as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. Previous testing of coibamide A in the NCI in vitro 60 cancer cell line panel revealed a potent anti-prolifera...

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Bibliographic Details
Main Authors: Andrew M Hau, Jeffrey A Greenwood, Christiane V Löhr, Jeffrey D Serrill, Philip J Proteau, Ian G Ganley, Kerry L McPhail, Jane E Ishmael
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3675158?pdf=render

Internet

http://europepmc.org/articles/PMC3675158?pdf=render

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