Exercise and the dipeptidyl‐peptidase IV inhibitor sitagliptin do not improve beta‐cell function and glucose homeostasis in long‐lasting type 1 diabetes—A randomised open‐label study

Exercise and the dipeptidyl‐peptidase IV inhibitor sitagliptin do not improve beta‐cell function and glucose homeostasis in long‐lasting type 1 diabetes—A randomised open‐label study

Abstract Background Increasing evidence points to beta‐cell regeneration in individuals with type 1 diabetes mellitus (type 1 DM) at all stages of the disease. Exercise and glucagon‐like peptide‐1 (GLP‐1) independently improve beta‐cell function and glucose homeostasis in animal studies and in clini...

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Bibliographic Details
Main Authors: Eleonora Seelig, Beckey Trinh, Henner Hanssen, Arno Schmidt‐Trucksäss, Helga Ellingsgaard, Mirjam Christ‐Crain, Marc Y. Donath
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Endocrinology, Diabetes & Metabolism
Subjects:
beta‐cell regeneration
dipeptidyl‐peptidase IV inhibitor
exercise
glucagon‐like peptide‐1
interleukin 6
type 1 diabetes mellitus
Online Access:https://doi.org/10.1002/edm2.75

Internet

https://doi.org/10.1002/edm2.75

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