Dysregulation of lncRNAs in Rheumatoid Arthritis: Biomarkers, Pathogenesis and Potential Therapeutic Targets

Dysregulation of lncRNAs in Rheumatoid Arthritis: Biomarkers, Pathogenesis and Potential Therapeutic Targets

Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology, mainly manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs), inflammation, synovial hyperplasia and cartilage erosion, accompanied by joint swelling and joint destruction. Abnormal expres...

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Bibliographic Details
Main Authors: Chenggui Miao, Liangliang Bai, Yaru Yang, Jinling Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
long noncoding RNAs
fibroblast-like synoviocytes
inflammation
epigenetic modification
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.652751/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.652751/full

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