Exploring two-photon optogenetics beyond 1100 nm for specific and effective all-optical physiology

Summary: Two-photon (2-P) all-optical approaches combine in vivo 2-P calcium imaging and 2-P optogenetic modulations. Here, firstly, we combined in vivo juxtacellular recordings and GCaMP6f-based 2-P calcium imaging in mouse visual cortex to tune our detection algorithm towards a 100% specific ident...

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Bibliographic Details
Main Authors: Ting Fu, Isabelle Arnoux, Jan Döring, Hendrik Backhaus, Hirofumi Watari, Ignas Stasevicius, Wei Fan, Albrecht Stroh
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001528