New ligands of the Cellular Retinoic Acid-Binding Protein 2 (CRABP2) suggest a role for this protein in chromatin remodeling

Retinoic acid (RA) regulates the transcription of a series of genes involved in cell proliferation, differentiation and apoptosis by binding to the RA Receptor (RAR) and Retinoid X Receptor (RXR) heterodimers. The cellular retinoic acid-binding protein 2 (CRABP2) is involved in the transport of RA f...

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Bibliographic Details
Main Authors: Daniella Barros Rossetto, Eric Nishimura Kiyomoto, Carlos Eduardo Brantis de Carvalho, Cleslei Fernando Zanelli, Sandro Roberto Valentini
Format: Article
Language:English
Published: São Paulo State University (UNESP) 2014-07-01
Series:Revista de Ciências Farmacêuticas Básica e Aplicada
Subjects:
Online Access:http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/110