Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients

Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients

<p>Abstract</p> <p>Background</p> <p>Assessment of T-cell diversity, besides giving insights about the molecular basis of tumor antigen recognition, has clinical implications since it provides criteria for evaluating antigen-specific T cells clinically relevant for spon...

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Bibliographic Details
Main Authors: Natali Pier, Palermo Belinda, Caimi Luigi, Sottini Alessandra, Serana Federico, Nisticò Paola, Imberti Luisa
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/21

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http://www.translational-medicine.com/content/7/1/21

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