Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice

Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice

Abstract Background Amyotrophic lateral sclerosis (ALS) is a disease characterized by a progressive degeneration of motor neurons leading to paralysis. Our previous MRI diffusion tensor imaging studies detected early white matter changes in the spinal cords of mice carrying the G93A-SOD1 mutation. H...

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Bibliographic Details
Main Authors: Rodolfo G. Gatto, Manish Y. Amin, Daniel Deyoung, Matthew Hey, Thomas H. Mareci, Richard L. Magin
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Translational Neurodegeneration
Subjects:
Amyotrophic Lateral Sclerosis
Spinal Cord
Ultra-high Field MRI
Diffusion Tensor Imaging
Yellow Fluorescent Protein
G93A-SOD1 mice
Online Access:http://link.springer.com/article/10.1186/s40035-018-0122-z

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http://link.springer.com/article/10.1186/s40035-018-0122-z

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