Active hippocampal networks undergo spontaneous synaptic modification.

The brain is self-writable; as the brain voluntarily adapts itself to a changing environment, the neural circuitry rearranges its functional connectivity by referring to its own activity. How the internal activity modifies synaptic weights is largely unknown, however. Here we report that spontaneous...

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Bibliographic Details
Main Authors: Masako Tsukamoto-Yasui, Takuya Sasaki, Wataru Matsumoto, Ayako Hasegawa, Takeshi Toyoda, Atsushi Usami, Yuichi Kubota, Taku Ochiai, Tomokatsu Hori, Norio Matsuki, Yuji Ikegaya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2082078?pdf=render