Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis

Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis

Autophagy plays an essential role in cell survival/death and functioning. Modulation of autophagy has been recognized as a promising therapeutic strategy against diseases/disorders associated with uncontrolled growth or accumulation of biomolecular aggregates, organelles, or cells including those ca...

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Bibliographic Details
Main Authors: Qingya Shi, Fen Pei, Gary A. Silverman, Stephen C. Pak, David H. Perlmutter, Bing Liu, Ivet Bahar
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
quantitative systems pharmacology
signal transduction
machine learning
drug-target interactions
mechanism of action
Online Access:https://www.mdpi.com/1422-0067/21/8/2855

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https://www.mdpi.com/1422-0067/21/8/2855

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