Fibroblast growth factor 21 promotes glucose uptake by a GLUT4-dependent and Akt-independent mechanism in isolated fibers of skeletal muscle

Fibroblast growth factor 21 promotes glucose uptake by a GLUT4-dependent and Akt-independent mechanism in isolated fibers of skeletal muscle

Introduction: Fibroblast growth factor 21 (FGF21) is a pleiotropic peptide hormone that induces glucose uptake in both primary myotubes and C2C12 myoblasts. However, the cellular mechanism involved and its role in adult skeletal muscle fibers is poorly understood. Material and Methods: Male mice we...

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Bibliographic Details
Main Authors: Giovanni Rosales-Soto, Alexis Díaz-Vegas, Paola Llanos, Mariana Casas, Enrique Jaimovich, Ariel Contreras-Ferrat
Format: Article
Language:Spanish
Published: Centro Nacional de Información de Ciencias Médicas. Editorial de Ciencias Médicas (ECIMED) 2020-01-01
Series:Revista Cubana de Investigaciones Biomédicas
Subjects:
fibroblast growth factor 21, glucose uptake, glut4-dependent and akt-independent mechanism, isolated fibers, skeletal muscle
Online Access:http://www.revibiomedica.sld.cu/index.php/ibi/article/view/457

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http://www.revibiomedica.sld.cu/index.php/ibi/article/view/457

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