Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy.
The detection of epistatic interactive effects of multiple genetic variants on the susceptibility of human complex diseases is a great challenge in genome-wide association studies (GWAS). Although methods have been proposed to identify such interactions, the lack of an explicit definition of epistat...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2669883?pdf=render |