Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy.

The detection of epistatic interactive effects of multiple genetic variants on the susceptibility of human complex diseases is a great challenge in genome-wide association studies (GWAS). Although methods have been proposed to identify such interactions, the lack of an explicit definition of epistat...

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Bibliographic Details
Main Authors: Wanwan Tang, Xuebing Wu, Rui Jiang, Yanda Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2669883?pdf=render