Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability

The numerous neurons and glia that form the brain originate from tightly controlled growth and division of neural stem cells, regulated systemically by important known stem cell-extrinsic signals. However, the cell-intrinsic mechanisms that control the distinctive proliferation rates of individual n...

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Bibliographic Details
Main Authors: Tamsin J Samuels, Aino I Järvelin, David Ish-Horowicz, Ilan Davis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
myc
Online Access:https://elifesciences.org/articles/51529