MicroRNA-488 and -920 regulate the production of proinflammatory cytokines in acute gouty arthritis

MicroRNA-488 and -920 regulate the production of proinflammatory cytokines in acute gouty arthritis

Abstract Background Gout is considered one of the most painful acute conditions caused by deposition of monosodium urate (MSU) crystals within joints. Recent studies have shown that interleukin (IL)-1β is a key inflammatory mediator in acute gouty arthritis (GA), and its level is regulated by microR...

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Bibliographic Details
Main Authors: Weidong Zhou, Ying Wang, Rongfeng Wu, Yan He, Qun Su, Guixiu Shi
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Arthritis Research & Therapy
Subjects:
MicroRNA
Gouty arthritis
Proinflammatory cytokines
Interleukin-1β
Monosodium urate crystals
Online Access:http://link.springer.com/article/10.1186/s13075-017-1418-6

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http://link.springer.com/article/10.1186/s13075-017-1418-6

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