Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells

Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells

Signal transducer and activator of transcription 3 (STAT3) andtelomerase are considered attractive targets for anticancertherapy. The in vitro anticancer activity of the gold(I) compoundauranofin was investigated using MDA-MB 231 human breastcancer cells, in which STAT3 is constitutively active. In...

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Bibliographic Details
Main Authors: Nam-Hoon Kim, Hyo Jung Park, Mi-Kyung Oh, In-Sook Kim
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-01-01
Series:BMB Reports
Subjects:
Antiproliferation
Auranofin
MDA-MB 231 cells
STAT3
Telomerase
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xJTVEMTMwMTI5MjEyMl8lMjgwNTktMDY0JTI5Qk1CXzEyLTEyMy5wZGY=

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http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xJTVEMTMwMTI5MjEyMl8lMjgwNTktMDY0JTI5Qk1CXzEyLTEyMy5wZGY=

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