Recent Insights into the Contribution of the Changing Hypertrophic Chondrocyte Phenotype in the Development and Progression of Osteoarthritis

Osteoarthritis (OA) is an extremely prevalent age-related condition. The economic and societal burden due to the cost of symptomatic treatment, inability to work, joint replacement, and rehabilitation is huge and increasing. Currently, there are no effective medical therapies that delay or reverse t...

Full description

Bibliographic Details
Main Authors: Ellen G. J. Ripmeester, Ufuk Tan Timur, Marjolein M. J. Caron, Tim J. M. Welting
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fbioe.2018.00018/full