The Mechanism by which 146-N-Glycan Affects the Active Site of Neuraminidase.

One of the most conserved glycosylation sites of neuraminidase (NA) is 146-N-glycan. This site is adjacent to the 150-cavity of NA, which is found within the active site and thought to be a target for rational drug development against the antiviral resistance of influenza. Here, through a total of 2...

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Bibliographic Details
Main Authors: Pi Liu, Zhonghua Wang, Lijie Zhang, Dongmei Li, Jianping Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4534095?pdf=render