Development and evaluation of a rapid analysis for HEPES determination in 68Ga-radiotracers

Abstract Background HEPES is a favorable buffer for 68Ga-complexations in radiochemical laboratories. The drawback of this buffer is its prescribed limit of 200 μg per recommended application volume in the final formulation. Currently, a TLC test according to the European Pharmacopoeia (Ph. Eur.) ha...

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Bibliographic Details
Main Authors: Sarah Pfaff, Tina Nehring, Verena Pichler, Jens Cardinale, Markus Mitterhauser, Marcus Hacker, Wolfgang Wadsak
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:EJNMMI Research
Subjects:
TLC
Online Access:http://link.springer.com/article/10.1186/s13550-018-0449-6