Electroporation facilitates introduction of reporter transgenes and virions into schistosome eggs.

The schistosome egg represents an attractive developmental stage at which to target transgenes because of the high ratio of germ to somatic cells, because the transgene might be propagated and amplified by infecting snails with the miracidia hatched from treated eggs, and because eggs can be readily...

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Bibliographic Details
Main Authors: Kristine J Kines, Gabriel Rinaldi, Tunika I Okatcha, Maria E Morales, Victoria H Mann, Jose F Tort, Paul J Brindley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2814865?pdf=render