Unfavorable Outcome of Neuroblastoma in Patients With 2p Gain

Unfavorable Outcome of Neuroblastoma in Patients With 2p Gain

Background: Amplification of the MYCN oncogene is the most unfavorable genetic factor in neuroblastoma patients. However, knowledge about the clinical impact of low-level multiplication of MYCN is still insufficient. Therefore, we aimed to investigate the disease course in patients with different co...

Full description

Bibliographic Details
Main Authors: Katarzyna Szewczyk, Aleksandra Wieczorek, Wojciech Młynarski, Szymon Janczar, Mariola Woszczyk, Zuzanna Gamrot, Radosław Chaber, Mariusz Wysocki, Monika Pogorzała, Mirosław Bik-Multanowski, Walentyna Balwierz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
2p gain
MYCN gain
MYCN amplification
neuroblastoma
structural chromosomal aberrations
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01018/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01018/full

Similar Items