Understanding the link between single cell and population scale responses of Escherichia coli in differing ligand gradients
We formulate an agent-based population model of Escherichia coli cells which incorporates a description of the chemotaxis signalling cascade at the single cell scale. The model is used to gain insight into the link between the signalling cascade dynamics and the overall population response to differ...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037015000446 |