Anti-Obesity Effects of Spiramycin In Vitro and In Vivo.

The effects of spiramycin on adipogenesis and high fat diet (HFD)-induced obesity were investigated. Potential mechanisms contributing to these effects were elucidated. The inhibitory effect of spiramycin on adipocyte differentiation was assessed using 3T3-L1 preadipocyte cells, in which several par...

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Main Authors: Mun Ock Kim, Hyung Won Ryu, Ji-Hee Choi, Tae Hyun Son, Sei-Ryang Oh, Hyun-Sun Lee, Heung Joo Yuk, Sungchan Cho, Jong Soon Kang, Chang Woo Lee, Jinhyuk Lee, Chong-Kil Lee, Sung-Tae Hong, Su Ui Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4939947?pdf=render