The Inhibitory Effect of Botulinum Toxin Type A on Rat Pyloric Smooth Muscle Contractile Response to Substance P In Vitro

The Inhibitory Effect of Botulinum Toxin Type A on Rat Pyloric Smooth Muscle Contractile Response to Substance P In Vitro

A decrease in pyloric myoelectrical activity and pyloric substance P (SP) content following intrasphincteric injection of botulinum toxin type A (BTX-A) in free move rats have been demonstrated in our previous studies. The aim of the present study was to investigate the inhibitory effect of BTX-A on...

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Bibliographic Details
Main Authors: Yu-Feng Shao, Jun-Fan Xie, Yin-Xiang Ren, Can Wang, Xiang-Pan Kong, Xiao-Jian Zong, Lin-Lan Fan, Yi-Ping Hou
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Toxins
Subjects:
botulinum toxin type A
substance P
electric field stimulation
neurokinin 1 receptor
antagonist of neurokinin 1 receptor
pyloric smooth muscle contractility
rat
Online Access:http://www.mdpi.com/2072-6651/7/10/4143

Internet

http://www.mdpi.com/2072-6651/7/10/4143

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