Paraoxonase Activity and Expression Is Modulated by Therapeutics in Experimental Rat Nonalcoholic Fatty Liver Disease

Objective. The objective of the present study is to investigate the effect of rosiglitazone, metformin, ezetimibe, and valsartan (alone or in combinations) on paraoxonase (PON) activity and PON-mRNA expression in nonalcoholic fatty liver disease (NAFLD). Methods. 54 Male Sprague–Dawley rats were div...

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Bibliographic Details
Main Authors: O. Hussein, J. Zidan, K. Abu Jabal, I. Shams, S. Szvalb, M. Grozovski, I. Bersudsky, R. Karry, M. Aviram
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Hepatology
Online Access:http://dx.doi.org/10.1155/2012/265305