Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells.

BACKGROUND: Many genome-wide association studies pointed out that SLC2A9 gene, which encodes a voltage-driven urate transporter, SLC2A9/GLUT9 (a.k.a. URATv1), as one of the most influential genes for serum urate levels. SLC2A9 is reported to encode two splice variants: SLC2A9-S (512 amino acids) and...

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Bibliographic Details
Main Authors: Toru Kimura, Michi Takahashi, Kunimasa Yan, Hiroyuki Sakurai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3883675?pdf=render