Polyethylene glycol-conjugated HER2-targeted peptides as a nuclear imaging probe for HER2-overexpressed gastric cancer detection in vivo

Polyethylene glycol-conjugated HER2-targeted peptides as a nuclear imaging probe for HER2-overexpressed gastric cancer detection in vivo

Abstract Background The human epidermal growth factor receptor 2 (HER2) involved proliferation, angiogenesis, and reduced apoptosis in gastric cancer (GC), which is a common target for tumor therapy. HER2 is usually overexpressed in more than 15% GC patients, developing a reliable diagnostic tool fo...

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Bibliographic Details
Main Authors: Siao-Syun Guan, Cheng-Tien Wu, Chen-Yuan Chiu, Tsai-Yueh Luo, Jeng-Yih Wu, Tse-Zung Liao, Shing-Hwa Liu
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
HER2 overexpression
HER2-targeted peptide
Nuclear medicine imaging
Online Access:http://link.springer.com/article/10.1186/s12967-018-1550-3

Internet

http://link.springer.com/article/10.1186/s12967-018-1550-3

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