A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial FunctionSummary

Background and aims: Gallstone disease (cholelithiasis) is a cholesterol-related metabolic disorders with strong familial predisposition. Mitochondrial DNA (mtDNA) variants accumulated during human evolution are associated with some metabolic disorders related to modified mitochondrial function. The...

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Bibliographic Details
Main Authors: Dayan Sun, Zhenmin Niu, Hong-Xiang Zheng, Fei Wu, Liuyiqi Jiang, Tian-Quan Han, Yang Wei, Jiucun Wang, Li Jin
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20301995