Immune-Inhibitory Gene Expression is Positively Correlated with Overall Immune Activity and Predicts Increased Survival Probability of Cervical and Head and Neck Cancer Patients

Immune-Inhibitory Gene Expression is Positively Correlated with Overall Immune Activity and Predicts Increased Survival Probability of Cervical and Head and Neck Cancer Patients

Background: Limited immunotherapy options are approved for the treatment of cervical cancer and only 10–25% of patients respond effectively to checkpoint inhibition monotherapy. To aid the development of novel therapeutic immune targets, we aimed to explore survival-associated immune biomarkers and...

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Bibliographic Details
Main Authors: Megha Budhwani, Gavin Turrell, Meihua Yu, Ian H. Frazer, Ahmed M. Mehdi, Janin Chandra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
cervical cancer
head and neck cancer
inflamed tumours
immune inhibition
immune checkpoints
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.622643/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.622643/full

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