Extensive purifying selection acting on synonymous sites in HIV-1 Group M sequences
<p>Abstract</p> <p>Background</p> <p>Positive selection pressure acting on protein-coding sequences is usually inferred when the rate of nonsynonymous substitution is greater than the synonymous rate. However, purifying selection acting directly on the nucleotide sequen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-12-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/5/1/160 |