Human fetal neural precursor cells can up-regulate MHC class I and class II expression and elicit CD4 and CD8 T cell proliferation

Human fetal neural precursor cells can up-regulate MHC class I and class II expression and elicit CD4 and CD8 T cell proliferation

The use of allogeneic fetal neural precursor cells (NPCs) as a cell replacement therapy in neurodegenerative disorders holds great promise. However, previous studies concerning the possibility of alloimmune rejection of the transplanted cells have been inconclusive. Here, we used flow cytometry to q...

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Bibliographic Details
Main Authors: R. Laguna Goya, R. Busch, R. Mathur, A.J. Coles, R.A. Barker
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Neurobiology of Disease
Subjects:
Fetal neural precursor cells
Cell replacement
Major histocompatibility complex
Immunogenicity
Proliferation assay
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110003426

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http://www.sciencedirect.com/science/article/pii/S0969996110003426

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